Massive stars are the cosmic engines that shape and drive our Universe. Many issues such as their formation, their stability and the mass loss effects, are far from being completely understood. Recent ground-based and space observations have shown pulsations in massive MS and post-MS stars, such as acoustic and gravity modes excited by the κ-mechanism and even solar-like oscillations. Theoretical studies emphasized the presence of strange modes in massive models, and recent theoretical analyses have shown that hot supergiants can pulsate in oscillatory convective modes. We review the instability domains of massive stars as well as their excitation mechanisms and present the latest results.