The horizontal branch (HB) morphology of globular clusters (GCs) is mainly described by metallicity. The fact that some clusters with almost the same metallicity exhibit different HB demonstrates that other parameters are at work. We present results from the analysis of the CMD of 72 GCs obtained with the Advanced Camera for Survey (ACS) of the Hubble Space Telescope (HST). We find a significant correlation between the HB color extension and the mass of the hosting cluster, while the color distance between the HB and the red-giant branch (RGB) depends on metallicity and age. We suggest that age and metallicity are the main global parameters of the HB morphology in GCs, while the HB extension is mainly due to internal helium variation, associated to multiple populations.